Abstracts of ISBM 2013 - 9th International Symposium on ...
2014-8-15 · Nicotine is metabolised to cotinine (COT) and further to trans-3'-hydroxycotinine (HCOT) by the cytochrome P450 CYP2A6 enzyme. It has been demonstrated that the …
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2014-8-15 · Nicotine is metabolised to cotinine (COT) and further to trans-3'-hydroxycotinine (HCOT) by the cytochrome P450 CYP2A6 enzyme. It has been demonstrated that the …
Get PriceThe ratio of trans-3'hydroxycotinine/cotinine (3HC/COT) is a marker of CYP2A6 activity, an important determinant of nicotine metabolism. This analysis sought to …
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Get PriceRequest PDF Assessing tobacco use in an African population: Serum and urine cotinine cut-offs from South Africa Cotinine, a nicotine metabolite, is used to …
Get Price2014-4-1 · Urinary COT, as the main metabolite of nicotine, was used as a biomarker for the assessment of direct or passive exposure to cigarette smoke. Even though most …
Get Price2013-4-26 · A rapid, sensitive and specific LC–MS-MS method was developed and validated for the determination of cotinine in human plasma, using a straightforward automated SPE …
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Get PriceMethods: This study involved a randomized, parallel arm design and six weeks of: (i) 0.05-0.09 mg nicotine yield cigarettes (N = 79); (ii) 21 mg nicotine patch (N = …
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